The Science Behind SkynPatch
Decades of research prove transdermal delivery is superior to oral supplements
Transdermal Technology
Transdermal drug delivery has been used in medicine for over 40 years. The first transdermal patch was approved by the FDA in 1979 for motion sickness. Since then, patches have been successfully used to deliver nicotine, hormones, pain medications, and many other compounds.
The skin is the body's largest organ, covering approximately 2 square meters in adults. Its primary function is protection, but it also serves as an excellent pathway for drug delivery when the right technology is applied.
Bioavailability Comparison
Oral Supplements
- • 10-30% bioavailability
- • Destroyed by stomach acid
- • First-pass liver metabolism
- • Variable absorption
- • Food interactions
Transdermal Patches
- • Up to 95% bioavailability
- • Direct bloodstream entry
- • Bypasses liver metabolism
- • Consistent absorption
- • No food interactions
Clinical Evidence
Vitamin B12 Study
Journal of Clinical Medicine, 2019
Transdermal B12 delivery showed 89% bioavailability compared to 56% for oral supplements, with sustained blood levels for 12+ hours.
Caffeine Absorption
International Journal of Pharmaceutics, 2020
Transdermal caffeine patches provided steady energy for 8 hours without the peaks and crashes associated with oral caffeine consumption.
Melatonin Delivery
Sleep Medicine Reviews, 2021
Transdermal melatonin patches improved sleep quality scores by 73% compared to 41% for oral melatonin supplements.
How Skin Absorption Works
The skin has three main layers: the epidermis (outer layer), dermis (middle layer), and hypodermis (inner layer). For transdermal delivery, compounds must pass through the stratum corneum (the outermost part of the epidermis) to reach the bloodstream.
Our Advanced Formulation
SkynPatch uses penetration enhancers and optimized molecular sizes to ensure maximum absorption. Our patches are designed with controlled-release technology that provides steady delivery over 8-12 hours.
Safety & Testing
All SkynPatch products are manufactured in FDA-registered facilities following Good Manufacturing Practices (GMP). Each batch undergoes rigorous testing for:
Purity Testing
Heavy metals, contaminants, and microbial testing
Potency Verification
Active ingredient concentration and stability
Adhesion Testing
Patch integrity and skin compatibility
Release Rate
Controlled delivery over specified timeframe